The Effect Of Sex On The Risk Of Cardiovascular Events Based On Serum Levels Of Total Cholesterol And Magnesium

Abstract

Cholesterol is a vital molecule that plays a pivotal role in several metabolic processes. It is the precursor to the synthesis of vitamin D, steroid hormones, and other substances. This molecule is transported through the blood by carriers called lipoproteins, namely CM, VLDL, LDL, and HDL. Magnesium ions play a crucial role in cholesterol and lipoprotein metabolism, and serum magnesium levels are inversely correlated with total serum cholesterol levels. Elevated LDL cholesterol levels are associated with cardiovascular disease.

This study included 85 male and 85 female participants. Venous blood samples were collected, and magnesium and total cholesterol levels were measured in the study participants using appropriate AMS kits. Magnesium levels were measured using the colorimetric method, while total cholesterol concentrations were measured using the enzyme-chromatographic method.

Our results indicated that serum magnesium levels were not statistically significant in males compared to females. However, this resulted in significantly higher serum total cholesterol levels, which (according to some recent studies) leads to higher LDL cholesterol levels and lower HDL cholesterol levels, thus increasing the risk of cardiovascular disease.