Comparison of Acute and Chronic Immunoglobulin (IgA, IgM, IgG) Concentrations in Relation to Middle ear Secretions in Adult Patients with Suppurative Otitis Media
Abstract
The research aimed to determine whether the concentrations of immunoglobulins IgA, IgG, and IgM in middle ear secretions are important in patients with suppurative otitis media by: studying the level of concentrations of immunoglobulins (IgA, IgM, IgG) in middle ear secretions in patients with otitis media. Acute and chronic suppurative disease in adults, and comparison between them.
The study was conducted on a sample of adults attending the ear department at Tishreen University Hospital in Lattakia with a history of purulent otitis media. The number of patients was (43) (7 acute otitis media - 36 chronic otitis media).
The results of the research showed that there is a statistically significant difference in the concentrations of immunoglobulin IgG (chronic inflammation is higher than acute inflammation), and there is a statistically significant difference in the concentrations of immunoglobulins IgM and IgA (acute inflammation is higher than chronic inflammation) in relation to middle ear secretions in adults.
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