Assessment of Effectivness of application of Hyaluronic Acid and Ozonated Olive Oil Mixture on Trismus Following Surgical Removal of Impacted Molars

Abstract

Introduction: Surgical extraction of impacted third molars is one of the most common procedures in oral surgery and is frequently associated with complications such as pain, swelling, and trismus. This study aimed to evaluate the efficacy of a topical blend of hyaluronic acid and ozonated olive oil in managing post-extraction trismus.

Materials and Methods: This randomized controlled split-mouth study included 18 patients who underwent bilateral surgical extraction of symmetrical impacted lower third molars under local anesthesia. Randomization was conducted via coin toss. One molar was treated with a hyaluronic acid and ozonated olive oil mixture before suturing, while the other served as a control. Trismus was assessed on postoperative days 3 and 7 using the independent t-test.

Results: The treatment group showed significantly greater mouth opening compared to the control, with p = 0.000 on day 3 and  p = 0.009 on day 7.

Conclusion: Topical application of a hyaluronic acid and ozonated olive oil blend is an effective method for reducing post-surgical trismus in mandibular third molar extractions.